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You have learned that the chemical nature of the side chains of amino acids (polar, nonpolar,...

Question:

You have learned that the chemical nature of the side chains of amino acids (polar, nonpolar, charged) is important in determining overall protein structure. Given this, why do you think that the addition of phosphate groups to proteins (as occurs during signal transduction) might affect protein structure/activity?

Amino Acid Side Chains:

Amino acid side chains are the side chains that give different amino acids their unique structural characteristics. As the name suggests, they are the chains attached at the side/s of the protein (specifically its backbone). They can be in relation to other chains as well to generate support for the overall structure of the protein. The side chains are classified as either polar, non-polar, or charged.

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Phosphorylation or the addition of phosphate groups to a protein can lead to a transient change in the structure of the protein. In this process, we...

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Amino Acid Side Chains: Function & Examples

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Chapter 5 / Lesson 18
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Proteins are constructed using amino acids that have side chains, which allow for unique chemical properties to be expressed. Explore four types of amino acid side chains: nonpolar, polar, basic, and acid.


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