Which of the following statements is NOT correct about the immunological incompatibility between mother and baby?
a. The baby's Rh+ blood will never get in contact with the mother's Rh- blood during the pregnancy as the placenta does not allow fetal blood cells to mix with the maternal blood.
b. If the baby is Rh+ and the mother is Rh-, it does not pose a problem as long as this is the mother's first pregnancy.
c. When the mother has Rh- blood, anti-Rh antibody injection is given during her pregnancy to prevent any antibodies from forming.
d. Rh- blood has no rhesus factor proteins and therefore will produce antibodies for the Rh factor when exposed to Rh+ blood.
Rh Blood Group:
The human blood group system discovered by Landsteiner and Weiner in the 1940s is named the Rh blood group system. It is determined concerning the presence or absence of D antigen proteins. These antigens are present on the surface of erythrocytes. The term Rh was designed as its determination test was done on the group of rhesus monkeys. The existence of D or Rh antigen in the blood makes an individual Rh-positive, while its absence makes the individual negative.
Answer and Explanation: 1
Erythroblastosis fetalis is a medical condition that arises due to the incompatibility within the ABO or the Rh blood group. The fusion of gametes of an Rh-positive father with an Rh-negative mother can lead to the production of an Rh-positive baby. Due to the lack of Rh antigens in the mother's body, the baby's D antigens will be treated as foreign substances. This can cause severe harm to the baby or even result in the termination of pregnancy in some cases.
The right answer is (a) The baby's Rh+ blood will never get in contact with the mother's Rh- blood during the pregnancy as the placenta does not allow fetal blood cells to mix with the maternal blood..
The Rh-negative mother is efficient in making antibodies against the Rh antigen present inside the child. The Rh antigens of the baby are considered harmful foreign substances. The antibodies formed by the mother tend to mix with the blood cells of the embryo by crossing the placenta. This can destroy the erythrocytes of the baby.
The condition of Rh incompatibility does not create a problem in the first pregnancy as the two types of blood rarely mix. There is a chance of their mixing only at the time of the child's delivery or any unfortunate leakage.
The Rh immune globulin antibodies are injected into the Rh-negative mother as a precautionary measure to avoid the production of antibodies against the child's blood.
The Rh-negative individual lacks the D antigen in them and considers these antigens as foreign substances. Thus, they produce antibodies when they are exposed to Rh-positive blood.
Learn more about this topic:
fromChapter 13 / Lesson 6
The Rh blood group system is a classification system for blood based on the presence or absence of Rh antigen. Individuals who possess the Rh antigen are considered Rh positive, whereas individuals who do not carry the antigen are considered Rh negative. Learn about blood groups, the Rh blood group system, Rh negative blood, and the effect of Rh factor in erythroblastosis fetalis.