What is role of topoisomerases in DNA supercoiling?


What is role of topoisomerases in DNA supercoiling?

DNA Supercoiling

DNA supercoiling exists in two forms that include toroidal and interwound supercoiling. DNA supercoiling gives an outlook of the DNA structure. Furthermore, DNA supercoiling is triggered by specific interacting proteins within the DNA. As a result, the double helix of the DNA appears bent.

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The role of topoisomerases in DNA supercoiling is to inhibit unnecessary supercoiling by cutting the existing DNA strands. Also, topoisomerase deals...

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Topoisomerase: Definition & Function


Chapter 17 / Lesson 6

Find out what topoisomerase is and its function in DNA replication. Discover the differences between topoisomerase 1 and topoisomerase 2 in DNA uncoiling.

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