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What does the term agglutination mean?

Question:

What does the term agglutination mean?

Biochemistry:

The scientific study that explores the chemical processes involving biological systems is known as biochemistry. Biochemistry itself is classified into various branches like animal biochemistry, enzymology, and plant biochemistry.

Answer and Explanation: 1

The term agglutination means clumping of free cells, bacteria, or some other particles. It is the interaction between an antibody and a particulate antigen (bacteria, WBC, RBC, latex particles). The antibodies, which are responsible for such reactions, are commonly known as agglutinin.

Agglutination is classified as either direct or indirect agglutination. Direct agglutination happens if the antigen is naturally present in the particle's (bacterium, virus, cell, etc.) surface, allowing these particles to bind directly with the antibodies and agglutinate thereafter. On the other hand, indirect agglutination happens if the particle needs to be "coated" first with a non-native antigen before the former is allowed to bind to an antibody for agglutination to occur.


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Agglutination in Microbiology: Definition & Examples

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Chapter 3 / Lesson 20
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Understand what agglutination is in microbiology by learning the definition and examining the examples, types, reactions, assay, and tests of agglutination.


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