What carbonyl compounds might you start with to prepare the following compounds by Grignard reaction? List all possibilities.
- a) 2-methyl-2propanal
- b) 1-ethylcyclohexanol
- c) 3-phenyl-3-pentanol
- d) 2-phenyl-2-pentanol
The Grignard reagent is formed by reacting an organomagnesium compound with haloalkane in ether solvent. The carbon atom of a Grignard reagent bears a partial negative charge and acts as a good nucleophile. Generally, Grignard reagents react with carbonyl compounds (aldehyde or ketone) to form alcohols.
- When reacted with formaldehyde, a primary alcohol is formed.
- When reacted with other aldehydes, secondary alcohols are formed.
- When reacted with ketones, tertiary alcohols are formed.
Answer and Explanation: 1
The following carbonyl compounds and Grignard reagents are needed to form alcohols:
See full answer below.
Become a member and unlock all Study Answers
Start today. Try it nowCreate an account
Ask a question
Our experts can answer your tough homework and study questions.Ask a question Ask a question
Learn more about this topic:
fromChapter 10 / Lesson 28
Learn about Grignard reactions with alcohol, ketone, and aldehyde. Study their mechanism and product, and discover which Grignard reaction turns ketone to alcohol.