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List the following carbonyl compounds in order of decreasing reactivity toward nucleophiles:...

Question:

List the following carbonyl compounds in order of decreasing reactivity toward nucleophiles: ester, acid chloride, amide, aldehyde, ketone.

Carbonyl Compounds

Carbonyl compounds are those compounds which contain one carbon-oxygen double bond.

Along with that one alkyl group is attached at the carbonyl carbon.

The second group attached to the carbonyl carbon can be hydrogen, alkyl group, -OH, -OR or {eq}-NH_{2} {/eq}.

Answer and Explanation: 1

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Order of reactivity towards nucleophiles is

{eq}-COCl\ >\ -CHO\ >\ -COR\ >\ -COOR\ >\ -CONH_{2} {/eq}

acid chlorides > aldehyde >...

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Carbonyl Group: Properties & Overview

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Chapter 4 / Lesson 11
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Learn about the carbonyl functional group and its properties. Study carbonyl group examples. See carbonyl compounds and understand the carbonyl structure.


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