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Laura, a high school volleyball player, went to visit her family physician because she has been...

Question:

Laura, a high school volleyball player, went to visit her family physician because she has been feeling fatigued, unwell, swollen ankles, and despite her workouts - she has gained 5 pounds this week. The doctor asks is she is taking any medications and Laura divulges that she has been taking about 3000mg of Ibuprofen per day for a knee injury she suffered during a match one month ago. Tests reveal that Laura's GFR is 25mL/min.

1. Based on her tests and symptoms - what condition is Laura now suffering from?

2. How did the excess Ibuprofen cause this condition? Be specific and discuss events at the glomerulus.

Edema:

Edema refers to a retention of fluid in the body. This can result in swelling, especially of the extremities like lower legs. Edema can result from a variety of conditions, including kidney failure and anemia.

Answer and Explanation: 1

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(1) Laura is most likely suffering from kidney failure. This is supported by her low glomerular filtration rate (GFR) (normal is around 90-120...

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Pathologies of the Kidneys

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Chapter 16 / Lesson 9
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Kidneys are designed to filter impurities out of the blood through urine, however, they sometimes fail in this task. In this lesson, learn about the signs and symptoms of kidney pathologies, conditions, and diseases.


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