How is transcription driven by phosphodiester bonds?


How is transcription driven by phosphodiester bonds?


It is one of the initial steps in the process of gene expression. The genetic information transfers from DNA to protein in a sequential process of transcription and translation. During the transcription process, just one strand of DNA is replicated, known as the template strand, and the RNA produced is known as the mRNA.

The primary goal of transcription is to create an RNA copy from the DNA sequence. The information used to encode a protein is carried by the RNA transcript.

Answer and Explanation: 1

The phosphodiester bond is created when a single phosphate or two pyrophosphates separate and catalyze the process. Two phosphates are removed when the phosphodiester bond develops between the 5' phosphate group of the new nucleotide and the 3' OH of the previous nucleotide in the DNA strand, giving energy for bonding.

The phosphodiester bond connects the 3' carbon atom of one sugar molecule to the 5' carbon atom of another, deoxyribose in DNA and ribose in RNA.

The "backbones of DNA and RNA" are made up of phosphodiester links. Thus, phosphodiester bonds play an important role in transcription.

Learn more about this topic:

Transcription Factors: Definition, Types & Roles


Chapter 18 / Lesson 5

What are transcription factors? This lesson will define transcription factors, discuss their functions, and their unique classes.

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