How do transcription factors affect gene expression, resulting in observable differences between...
Question:
How do transcription factors affect gene expression, resulting in observable differences between individuals within a population?
They act as repressors that increase gene expression by binding to DNA.
They bind to operons and activate transcription to decrease gene expression.
They bind to regulatory proteins and act as activators to increase gene expression.
They inhibit transcription and decrease gene expression by binding to repressors.
Transcription:
Transcription is the first step in gene expression, which occurs when information stored in DNA is used to make a protein. In transcription, a DNA sequence is copied, or transcribed, into a molecule of mRNA.
Answer and Explanation: 1
The correct answer is: They bind to regulatory proteins and act as activators to increase gene expression. Transcription factors are proteins that bind to DNA sequences in order to activate the transcription of genes. Once bound to the DNA, transcription factors also interact with and bind to other regulatory proteins in order to recruit RNA polymerase, the enzyme that catalyzes transcription. By promoting transcription, these factors also promote gene expression.
Ask a question
Our experts can answer your tough homework and study questions.
Ask a question Ask a questionSearch Answers
Learn more about this topic:

from
Chapter 18 / Lesson 5What are transcription factors? This lesson will define transcription factors, discuss their functions, and their unique classes.
Related to this Question
- If a transcription factor causes more frequent gene expression of gene A in one cell, what do you expect to happen in the cell? A). an increase in the amount of mRNA for gene A in that cell only. B). an increase in the number of ribosomes in the cell.
- If a transcription factor causes more frequent gene expression of gene A in one cell, what do you expect to happen in the cell? A. an increase in the amount of mRNA for gene A in that cell only. B. an increase in the number of ribosomes in the cell. C. an
- What would be the impact of a mutation that eliminates transcription factor (tf3) on the expression of gene 2 (g2)? A. It would produce more transcripts if tf1 and tf2 were active. B. It would be inactivated. C. If it has a strong promoter, it will be con
- Describe some of the general ways in which (specific) transcription factors are regulated and how they, in turn, can regulate gene expression
- The structure of DNA is one factor which regulates gene expression (replication and transcription). Explain how the structure of DNA allows transcription to occur. Why is the configuration of DNA important for gene expression?
- How does gene expression influence the behavior of cells that contain the same genome (genetic information)? How has genetic engineering impacted humans? Be specific in your answer.
- What features of DNA or transcription allow variation in the quantity of expression of a gene?
- (a) What is a transcription factor? (b) How do multiple transcription factors interact to result in the activation of transcription for a particular gene?
- Do methylation patterns on DNA change during one's lifetime? How would that affect gene expression?
- A mutation has occurred in the promoter sequence of a gene. Briefly explain what effect that mutation will likely have on the transcription of the gene.
- Explain why many developmental genes encode either transcription factors or signaling factors.
- How can enhancers influence the transcription of genes that are really far away on the same chromosome?
- Describe the process of gene expression, from gene to protein, and how a gene affects the phenotype expressed by an organism.
- (a) How does DNA methylation affect gene expression? (b) What characteristic of DNA allows methylation patterns to be maintained through replication and cell division?
- 1. How does heterochromatin and euchromatin affect gene expression? 2. Explain if this method typically causes an increase in gene expression, a decrease in gene expression, or might cause either. Be sure to explain why.
- How do microRNA molecules help regulate gene expression? a. They inhibit translation by folding themselves in a process called RNA interference b. They repress gene expression by preventing transcription factors from binding to DNA. c. They modify fini
- If mutation occurs causing transcription of a gene to occur on both strands of the DNA in the same cell, what affect would you expect that to have on the production of protein for the gene?
- Explain what transcription factors and regulatory proteins are and how they regulate gene expression in eukaryotes.
- Explain the potential influence of mutations on the quality of the protein-DNA interactions and the potential impact of these mutations on gene expression.
- What is the role of transcription factors? A) Add a "cap" and "tail" to mRNA B) AInitiate gene expression C) Break apart old mRNA polymers D) Control the modification of proteins
- What is epigenetics? How does it relate to gene expression?
- What is epigenetics, and how does it relate to gene expression?
- If a mutation damaged the enhancer regulatory element in a eukaryotic gene promoter, how would this affect the transcription of the gene? (a) The rate of transcription would be very low. (b) The transcriptional start site would be shifted. (c) The promot
- The maternal effect bicoid protein is a transcription factor that binds to the promoter of a zygotic gene to activate its expression. What is this second gene?
- Explain how our genes control our traits with a specific example. Your explanation should contain the following words: transcription, translation, gene, mRNA, and protein.
- How can changes in transcription lead to phenotypic variation without changes in a DNA sequence?
- What is the effect of methylating DNA on gene expression? a. Methylation improves access of RNA polymerase enzymes to genes. b. It acts as an enhancer. c. Methylation keeps DNA tightly bound to histone proteins, making genes unavailable for transcripti
- Explain why eukaryotic gene expression requires proteins in addition to the six general transcription factors.
- Which type of receptor also functions as a transcription factor to induce gene expression?
- What is methylation and how does it cause an effect on gene expression?
- Modifications of histone tails can: a. affect chromatin structure. b. activate transcription of some genes. c. repress transcription of some genes. d. affect expression of some genes in response to the environment. e. All of these choices are correct.
- You have isolated a novel transcription factor. How will you determine the genes regulated by the transcription factor in the whole genome? How will you determine the transcription factor binding sites in the whole genome?
- Certain lysine amino acids in the core histone tail can be acetylated. How would this chemical modification of the nucleosome affect the transcription of a gene?
- How will the following mutations affect transcription initiation of the trip operon? \\ A. A mutation that deletes that trpR gene B. A mutation that deletes trpO C. A mutation that prevents the trypressor from binding tryptophan
- How do enhancer elements work to regulate transcription of certain genes at specific times and places? A. By initiating the attachment of RNA polymerase to the start codon of the gene. B. By removing histones from blocking DNA transcription. C. By servin
- Generally, what are the differences in how steroid versus protein hormone signals are transduced (signal ultimately affects gene transcription)?
- Describe the stages of gene transcription. Genes have special internal DNA sequences that form hairpins and specify a transcription pause. Explain in a mechanistic manner how these sequences affect the rate of transcription and discuss their potential ben
- What effect would the deletion of a single nucleotide in a DNA sequence encoding a gene affect the process of transcription and the resultant mRNA sequence?
- Regulation of expression by transcription factors and by alternative splicing are two different mechanisms of controlling gene expression in eukaryotes. What is the fundamental difference between the two?
- Describe the regulation of gene transcription, especially the involvement of various DNA sequence elements, protein factors, and non-protein factors in the regulation process.
- Describe how chromatin structure (DNA methylation and histone modification) can affect gene expression.
- How do epigenetic influences change how the DNA strand is read? Provide at least two specific examples.
- Gene expression consists of two major processes: transcription and translation. Describe both of these processes from binding of the DNA by transcription factors to release of ribosomes following a stop codon. Unlike in eukaryotes, these processes can occ
- What are the effects of a DNA mutation on gene expression?
- Describe how controlling gene expression will alter the overall protein levels in the cell.
- Epigenetic changes affect gene expression. What part of the chromatin (or the chromosome) is affected by epigenetic changes?
- Which of these factors does not influence the rate of mutation? (a) The presence of a repetitive sequence. (b) The protein encoded by the gene. (c) The presence of a palindrome. (d) A gene's length. (e) The ability to repair DNA.
- You have isolated a novel transcription factor. How will you determine the genes regulated by the transcription factor in the whole genome?
- If an individual has a mutation in the genes that codes for DNA polymerase, what effect would this have on transcription? (a) It would be halted. (b) It would be slowed. (c) It would occur faster. (d) It would have no effect. (e) You need more information
- A bacterial strain has a mutation in the TRP repressor which prevents the protein from ever binding tryptophan. How would you predict this mutation would affect expression of the TRP operon?
- How can a transposon influence the expression of a gene?
- Why does a genetic abnormality affect protein synthesis? a. The genetic sequence controls the expression of genes. b. Nucleotide sequences create proteins. c. Protein synthesis does not respond to change during expression. d. Correct genetic sequences det
- Explain how the sequence of DNA impacts the function of the gene.
- What is the difference between a gene and an allele and how might protein synthesis execute differently if a mutation occurs?
- Transcription factors (proteins) help our cells to promote gene expression (e.g., the production of insulin) by binding directly to DNA and by assisting _____ to initiate transcription. a) Actin monomers b) Tight junctions c) RNA polymerases d) Muscle fib
- One way mutations can affect the phenotype is by altering the coding sequence of a gene and therefore changing protein structure. Describe two ways that mutations can affect the phenotype that does not include alteration of the protein coding sequence.
- What general transcription factors associate with an RNA polymerase II promotor in addition to the polymerase? In what order do they bind in vitro? What structural change occur in the DNA when an "open" transcription initiation complex is formed?
- Outline reasons why changes to the DNA sequence within the protein-encoding regions of a gene may not result in a disease phenotype.
- If a mutation occurred that increased the number of introns in a sequence of DNA, what impact would this have on the protein formed from the gene? A. It would change the shape. B. It would change the function. C. it would have no effect. D. Both A and B
- What is acetylation and how does it cause an effect on gene expression?
- Explain how CREB protein is being regulated to activate gene transcription and how a specific transcription control gene expression? Name each step.
- Nuclear receptors can regulate gene expression by recruiting transcription factors that promote which of the following? A. Transcription B. Transcript elongation C. RNA splicing D. RNA transcription termination E. All of the above
- Explain how one type of mutation might affect the protein produced by a given gene in a bad, good, and neutral way. Explain the effect at each step of transcription and translation.
- In what specific ways can chromatin structure be modified, and how do these modifications influence eukaryotic gene expression?
- How is the rate of transcribed mRNA from a particular gene is controlled? Explain.
- What effect does methylation have on gene expression?
- Eukaryotes have 3 RNA polymerases that transcribe unique sets of genes. What genomic feature confers specifically and determines whether a gene is transcribed by RNA Pol I, II or III? a. promoter b. start codon c. enhancer d. +1 nucleotide e. polyA sequen
- Aside from DNA methylation, what other types of epigenetic modifications can occur within the genome to influence gene expression?
- Are transcription factors required for transcription in eukaryotes or can RNA polymerase bind to the promoter of a gene by itself?
- What is the role of transcription factors? a. binding heterochromatin to prevent transcription b. binding promoter of a gene to start translation c. binding promoter to start transcription d. binding operator to prevent transcription e. binding repressor
- Steroid hormones affect gene expression by: a. Changing the level of histone methylation b. Binding to steroid hormone receptors, which are transcription factors c. Altering DNA methylation d. Binding to RNA polymerase II e. Triggering a protein kinase ca
- In general terms, what are the two factors required to activate gene transcription?
- How does a genetic mutation occur? a. Base pairs are deleted or inserted along with the DNA. b. The nucleus signals for a mutation to occur. c. Introns are removed from the genetic sequence. d. Genetic mutations occur systematically.
- How does genome packaging lead to epigenetic effects and epigenetic inheritance?
- Define epigenetic control. Explain how it alters gene transcription and translation.
- Geneticists compare DNA base sequences among organisms and use this data to determine a gene's rate of evolution. Different genes have been found to evolve at different rates. Explain why some genes might have faster rates of evolution than other genes as
- Why has the One Gene - One Polypeptide hypothesis been modified? a. Genes can be spliced differently to generate a variety of related polypeptides. b. Enzymes sometimes consist of more than one polypeptide, each of which is coded for by its own gene. c. E
- In general terms, explain how chromatin organization can regulate gene expression at the transcription level.
- DNA binding domains in transcription factors allow: a. Transcriptional termination b. Binding of a given transcription factor to specific sequences c. The transcription factor to form dimers d. Transcription factors to bind to splice junctions
- How are genes (and therefore protein production) regulated? Select one: a. they aren't, all proteins are constantly transcribed b. mutations in the DNA cause genes to turn on and off c. regulatory proteins interact with DNA to speed up or slow down produc
- What is the process in which the general transcription factor bind to specific sites on DNA to activate transcription of genetic information from DNA to messenger RNA?
- How is the information encoded in the RFP gene expressed as a trait? Be sure to use what you have previously learned about gene expression and the relationship between DNA, RNA, proteins, and traits.
- In mammals, the action of modifying gene expression in which one X chromosome is inactivated in the cell of females differs from how miRNA performs gene silencing in that: a. miRNA blocks transcription factors. b. miRNA is a method of posttranscriptional
- How does activation of the Ras protein in the FGF signaling pathway lead to changes in gene transcription?
- eukaryotic gene regulation: \\ Transcription factors are sometimes activated by phosphorylation as in the MAPK pathway. Explain how this links an extracellular hormone signal to eukaryotic gene transcription. Be specific.
- Enzymatic activity can be regulated by gene transcription. Explain how this influences the activity of enzymes in general.
- Which of the following does NOT regulate gene expression after transcription? a. MicroRNA b. Translational repressor proteins c. Modifications to the 5 cap d. Alternative splicing e. Transcription fac
- What are the 2 ways in which a miRNA can regulate gene expression?
- Briefly explain how a point mutation in the DNA sequence of a gene can alter the function of the protein product of that gene.
- What determines where in the genome a transcription regulator will bind? a. Transcription regulators bind to the 5' UTR region of a gene. b. Regulators bind via complementary base-pairing to certain DNA molecules. c. Covalent bonds form between the trans
- Explain how eukaryotic gene expression occurs at the epigenetic, transcriptional, post-transcriptional, translational, and post-translational levels.
- How do mutations in protein coding genes and regulatory DNA contribute to evolution? How is the genetic basis of life a central role of biotechnology?
- Nuclear receptors can regulate gene expression by recruiting transcription factors that promote a) Transcription b) Transcript elongation c) RNA splicing d) RNA transcription termination e) All of the above
- In an operon that is under positive repressible control, what would be the effect on gene expression if the gene that codes for the regulatory protein is changed so that the regulatory protein no longer binds DNA? A) the operon would always be off B) the
- Construct an explanation based on evidence for how the structure of DNA in a regulatory region determines the expression of proteins that further affect the expression of other genes.
- Select the correct answer. Enhancers are: a. Transcription factors. b. Sequences of DNA that help to determine expression of a transcript. c. Nonsense mutations. d. None of the above.
- What is a common technique used to identify all the target genes of the transcription factor E2F?
- Explain in your own words three ways in which mutations outside the gene can affect protein function or structure.
- How do chemical mutagens interfere with DNA replication or gene expression?
- What is the process that turns on the transcription of a gene or genes?