Based on your understanding of gene regulation in the cell and the function of the trp operon,...
Question:
Based on your understanding of gene regulation in the cell and the function of the trp operon, describe how this process would be affected if there was a mutation in the operator region so that the operator could not carry out its function.
Operons
Operons are clusters of protein-coding, or structural, genes that have a related function. The protein-coding genes share a common promoter from which RNA polymerase initiates transcription. A cis-regulatory sequence known as the operator is located between the promoter and the structural genes. The operator is the binding site for a regulatory protein that represses transcription from the promoter.
Answer and Explanation: 1
Become a Study.com member to unlock this answer! Create your account
View this answerA mutation in the trp operator that destroys its function would be one that changes its sequence so that the repressor protein does not recognize and...
See full answer below.
Ask a question
Our experts can answer your tough homework and study questions.
Ask a question Ask a questionSearch Answers
Learn more about this topic:

from
Chapter 9 / Lesson 4Understand what a lac operon is and its function, diagram, and structure. Know more about lac operon regulation through transcriptional repression and induction.
Related to this Question
- Answer of the following question. Describe how the trp operon functions in prokaryotic gene transcription.
- Using the lac operon as an example, explain the concept of an inducible operon. Discuss the functions of the following in controlling the expression of the lac operon: regulatory gene, promoter, operator, genes of the operon, repressor, and the inducer,
- Explain the regulation of gene expression in bacteria in a/an: (a) inducible operon (b) repressible operon.
- The rate of transcription of the trp operon in E. coli is controlled by what two regulatory processes? These two processes can regulate the trp operon up to about _____-fold due to the combined effects of these processes. By what mechanisms do these two r
- Describe how controlling gene expression will alter the overall protein levels in the cell.
- Explain what transcription factors and regulatory proteins are and how they regulate gene expression in eukaryotes.
- Briefly explain how a point mutation in the DNA sequence of a gene can alter the function of the protein product of that gene.
- The regulatory gene that codes for the tryptophan repressor is not tightly linked to the trp operon. Would it be advantageous if it were? Explain your answer.
- A bacterial strain has a mutation in the TRP repressor which prevents the protein from ever binding tryptophan. How would you predict this mutation would affect expression of the TRP operon?
- Describe the process of gene expression, from gene to protein, and how a gene affects the phenotype expressed by an organism.
- Describe how acetylation and methylation of proteins contribute to epigenetic regulation of gene expression.
- If the tryptophan repressor is not able to bind to the operator site, in an trp operon, how would that effects the behavior of E. coli?
- The number and type of proteins found in a cell can be influenced by genetic mutation and regulation of gene expression. Explain how these two processes differ.
- What would happen if there was a mutation in the operator of the trp operon?
- Explain what an activator is and how such proteins can regulate gene expression. You should include in your answer details of the genetic elements activators can bind to and outline two different molecular mechanisms by which activators can influence gene
- Describe some of the general ways in which (specific) transcription factors are regulated and how they, in turn, can regulate gene expression
- Explain the two mechanism that miRNA can regulate gene expression.
- How is the operator switch turned on and off in the expression of genes in the lac operon? Explain.
- Explain how gene regulation in eukaryotes differs from gene regulation in prokaryotes.
- Explain gene regulation: a. How does a gene get turned on? b. How does a gene get turned off? c. Why aren't all genes on in all cells?
- In an operon that is under negative inducible control, what would be the effect on gene expression if the gene that codes for the regulatory protein is changed so that the regulatory protein cannot bind DNA? A) the operon would always be on B) the operon
- Why is an understanding of gene regulation in eukaryotes crucial to an understanding of developmental processes?
- Explain the process of RNA interference and how it regulates gene expression.
- a. Explain what an operon is. b. How do inducible operons (e.g., the lactose operon) and repressible operons (e.g., the tryptophan operon) benefit a bacterial cell?
- Describe the process of gene regulation in eukaryotes.
- In an operon that is under positive repressible control, what would be the effect on gene expression if the gene that codes for the regulatory protein is changed so that the regulatory protein no longer binds DNA? A) the operon would always be off B) the
- Construct an explanation based on evidence for how the structure of DNA in a regulatory region determines the expression of proteins that further affect the expression of other genes.
- Explain the regulation of gene expression in eukaryotic cells.
- Define epigenetics, describe how it affects gene regulation and how it is related to the onset of disease/disorders. How is it different than DNA mutations? Explain two examples of epigenetic mechanisms and their effects on gene regulation.
- Explain how prokaryotic genes are expressed in an operon model. Include the three major components and their roles.
- Explain mechanisms with which eukaryotes control gene expression.
- Explain how CREB protein is being regulated to activate gene transcription and how a specific transcription control gene expression? Name each step.
- How do mutations in protein coding genes and regulatory DNA contribute to evolution? How is the genetic basis of life a central role of biotechnology?
- Explain how our genes control our traits with a specific example. Your explanation should contain the following words: transcription, translation, gene, mRNA, and protein.
- Explain the fundamentals of epigenetic gene regulation. At the molecular level, discuss the different mechanisms that can influence gene regulations.
- Explain how a cell can control the expression of the lacZ gene.
- Discuss the roles of histone proteins with regard to eukaryotic gene expression and regulation.
- What is the function of the following elements of an operon? a) regulator b) operator c) promoter d) structural genes
- Describe two ways in which eukaryotes regulate gene expression inside of the nucleus and two ways in which they regulate gene expression outside of the nucleus.
- What is positive gene regulation? a. when an activator protein binds to the operator of a gene to turn expression off b. when a repressor protein binds to the operator of a gene to turn expression off c. when an activator protein binds to the operator of
- Define the different elements of the Operon - promoter, operator, and structural genes. Do all of these code for proteins or RNA? What is the function of each?
- Describe the mechanism of recombination and describe the role of this process in genome evolution.
- Describe the regulation of gene transcription, especially the involvement of various DNA sequence elements, protein factors, and non-protein factors in the regulation process.
- Describe the differences in gene expression control between a repressible and an inducible bacterial operon.
- Explain the inducible operon and repressible operon system, also explain these two systems by giving suitable examples.
- Explain in your own words three ways in which mutations outside the gene can affect protein function or structure.
- (a) Explain how mutations can lead to the evolution of new functions for the protein encoded by the mutated gene. (b) Does the mutation need to be located in the coding sequence to generate a new function?
- Explain how transcription, phosphorylation, protein-protein interactions, and proteasome-mediated turnover are involved in cell cycle regulation (like G1,S,G2,M Phases).
- Explain what an operon is and explain how the lac operon works.
- How does an operon enable specific and efficient regulation of a group of genes?
- How is the control gene of the arabinose operon different from the lactose operon?
- Describe how transcription, phosphorylation, protein-protein interactions and proteasome-mediated turnover are involved in cell cycle regulation.
- Describe transcription control in the Arabinose (araBAD) operon.
- A mutation has occurred in the promoter sequence of a gene. Briefly explain what effect that mutation will likely have on the transcription of the gene.
- How gene control in a non-inducible system might be achieved?
- Discuss gene expression and describe the functions of various non-coding RNAs.
- (a) What is a gene? (b) Describe the function, structure, and location within the cell.
- What is a gene? Describe the function, structure, and location within the cell.
- Briefly describe how transcription, phosphorylation, protein-protein interactions, and proteasome-mediated turnover are involved in cell cycle regulation.
- Describe and assess the role of transformation as a genetic recombination mechanism.
- Suppose you know the amino acid make-up of specific proteins in a cell. How would you determine the particular DNA code that coded for them. Explain how one change in a DNA nucleotide could alter the formation of the translated protein AND what effect it
- (a) Describe gene regulation in prokaryotes and eukaryotes. (b) Why it is important to each of them?
- 1. Explain how the code that is found in the organism`s genes works. 2. Describe how the genetic code controls the production of proteins. 3. Find diagrams to help explain.
- Be able to describe the function of all the proteins in the replisome - what would happen if there was a mutation in any one of these proteins?
- Briefly explain why silent mutations in the DNA sequence of a gene do not alter the function of the protein product of that gene.
- How is gene regulation in prokaryotes different from eukaryotes? a. Prokaryotes rely almost exclusively on homeotic genes to regulate expression. b. Prokaryotes (unlike eukaryotes) regulate transcription by use of operons. c. Prokaryotes can regulate t
- In general terms, explain how chromatin organization can regulate gene expression at the transcription level.
- Briefly describe 6 different ways that cells typically regulate gene expression.
- Explain how the sequence of DNA impacts the function of the gene.
- Explain how DNA methylation can regulate gene expression in a tissue-specific way.
- Define epigenetic control. Explain how it alters gene transcription and translation.
- Chromatin dynamics (i.e., higher-order structure of chromatin) affects gene expression. Describe how the mitochondrial genome is organized and how regulation of mitochondrial gene expression is accomplished.
- Explain the role of repressor in the case of the lac operon.
- How does the regulation of histones and chromatin control gene expression? What are the functions of HATs, HDACs, and methyltransferases?
- A) Explain the meaning of "Gene Expression". B) Explain why regulation of gene expression is important in (i) unicellular (single-cell) organisms and (ii) multicellular organisms.
- What is the difference between a gene and an allele and how might protein synthesis execute differently if a mutation occurs?
- An operon is a. a repressor that binds to a promoter. b. a molecule that switches a gene off or on. c. a gene that cannot be repressed or enhanced. d. a functional unit of promoter, operator, and structural genes in bacteria. e. none of the above.
- Explain what Tsix is in genes and its role in either the translation, transcription, or replication process of the cell.
- How are genes (and therefore protein production) regulated? Select one: a. they aren't, all proteins are constantly transcribed b. mutations in the DNA cause genes to turn on and off c. regulatory proteins interact with DNA to speed up or slow down produc
- What are some ways that eukaryotic gene expression can be regulated?
- How is chromatin state controlled? What features distinguish euchromatin from heterochromatin? What gene expression profiles and histone modification profiles are associated with each?
- a) Identify, and explain at least 4 actions that can result in changes in chromosome structure. b) Explain why changes in nucleotide sequence could result in the production of different proteins.
- How do transcription factors affect gene expression, resulting in observable differences between individuals within a population? \\ They act as repressors that increase gene expression by binding to DNA. \\ They bind to operons and activate transcripti
- Explain how one change in a DNA nucleotide could alter the sequence of amino acids in the resulting protein. (An example would be the difference between normal and sickle-cell hemoglobin.)
- Describe the mechanism of gene segment rearrangement and receptor diversity.
- Describe how chromatin structure (DNA methylation and histone modification) can affect gene expression.
- eukaryotic gene regulation: \\ Transcription factors are sometimes activated by phosphorylation as in the MAPK pathway. Explain how this links an extracellular hormone signal to eukaryotic gene transcription. Be specific.
- In a prokaryotic operon, genes that code for enzyme proteins are called a. structural genes. b. operator genes. c. repressor genes. d. inducer genes. e. regulatory genes.
- Describe how the lac operon is controlled.
- Which of the following genes is located outside the operon and codes for a repressor protein that can deactivate the operon? a. structural gene b. promoter gene c. regulatory gene d. homeotic gene e. operator gene
- Explain mechanisms by which gene expression may be altered. How do these alterations induce cancer-causing mutations in cell DNA?
- What is a regulatory region in DNA and how can it control gene expression?
- Outline reasons why changes to the DNA sequence within the protein-encoding regions of a gene may not result in a disease phenotype.
- 1. How does heterochromatin and euchromatin affect gene expression? 2. Explain if this method typically causes an increase in gene expression, a decrease in gene expression, or might cause either. Be sure to explain why.
- Explain the roles of cell signaling in DNA, transcription, and protein synthesis.
- How do chromatin modifications regulate transcription? What modifications are observed in regions of the genome that are being transcribed? In regions that are not actively transcribed?
- In the lactose operon of E. coli, the operator is: Select one: a. A regulatory region to which RNA polymerase binds. b. A regulatory region to which the repressor binds c. A regulatory region to which CRP binds d. A repressor protein
- What is an operon? In what type of organism would you expect to find an operon? Give an example of an inducible operon, describe the overall function of the gene(s) it encodes, and how it is regulated. How is an operon typically organized? Describe a type
- Geneticists use the tryptophan operon as a model of attenuation. Attenuation further decreases the activity of the operon when the end product, tryptophan, is available. Diagram and explain how the mechanism of attenuation is dependent on the translation
- a) Describe and explain the mechanisms in which DNA is used to generate protein. b) Identify and explain any major differences between the mechanisms in prokaryotic and eukaryotic cells.